New research from CSHL Associate Professor Tobias Janowitz, WashU Medicine Professor Adam Kepecs, and their collaborators reveals a circuit in the brainstem that can sense inflammation and drive apathy-like behavior in cancer cachexia. Janowitz is a co-team lead for CANCAN, tackling the cachexia challenge set in 2020 by Cancer Grand Challenges, a research initiative co-founded by Cancer Research UK and the National Cancer Institute.